Trump Launches 'Genesis Mission' to Centralize AI Resources for Scientific Research

President Trump on Monday signed an executive order creating the "Genesis Mission," a new federal initiative designed to expand and centralize artificial intelligence resources for scientific research.

What the Genesis Mission will do

The administration likens the effort to the Apollo program of the 1960s. The Genesis Mission aims to build an integrated AI platform that links federal datasets, high-performance computing capacity and AI tools to accelerate discoveries across fields such as drug development, materials science and climate modeling.

American Science and Security Platform

The order directs the Energy Department to establish and operate the "American Science and Security Platform," described by the White House as a "closed-loop AI experimentation platform." The platform will consolidate National Laboratory resources — including supercomputing, AI modeling and analysis frameworks, domain-specific foundation models, computational tools and secure access to datasets — into a shared environment for researchers.

Leadership, priorities and partnerships

Energy Secretary Chris Wright has been tasked with running the platform, compiling a list of "science and technology challenges of national importance," assessing federal computing capabilities and pursuing public-private partnerships to expand capacity. Wright pointed to newly announced projects involving Nvidia, AMD and HPE with the National Laboratories as examples of that collaboration.

Michael Kratsios, director of the White House Office of Science and Technology Policy, told reporters: "Since the 1990s, America's scientific edge has faced growing challenges — new drug approvals have flatlined or declined, more researchers are needed to achieve the same output and workforce training has stagnated. Genesis Mission aims to overcome these challenges by unifying agency scientific efforts and integrating AI as a scientific tool to revolutionize the way science and research are conducted."

Energy Secretary Chris Wright said the initiative is part of a broader push to improve efficiency and affordability: "What does innovation and improvement drive? It drives efficiency. We want the federal government to work better, to work faster, more accurately and more efficient for the American people... More production, less cost, lower prices."

Context and outlook

Officials say the Genesis Mission is tied to the administration's recent emphasis on affordability and improved government performance following the off‑year elections. The executive order sets a framework for centralizing AI-enabled research tools, but details such as timelines, budgets and specific access policies for outside researchers will be defined as the Energy Department implements the platform.

Observers say the program could accelerate scientific workflows if it succeeds in providing secure, user-friendly access to powerful computing and curated datasets. Critics may push for clear governance, data privacy protections and transparency around partnerships as the initiative moves forward.