Researchers at the University of Vermont analyzed a subset of the REGARDS cohort and found that three blood biomarkers — NfL, GFAP and UCH-L1 — predicted later memory problems over roughly 12 years. The results suggest that blood tests could identify dementia risk decades before symptoms emerge. Early detection could guide preventive lifestyle changes and future treatments, but the tests require further validation before clinical use.
Blood Tests May Predict Dementia Risk Decades Before Symptoms, UVM Study Finds
08:40 PM, 11/21/2025
Similar Articles
Pinprick blood test could detect diseases up to 10 years before symptoms, new UK Biobank dataset suggests
The UK Biobank and Nightingale Health have released a final dataset of nearly 250 blood metabolites measured in about 500,000...
Study: Memory 'Fuzziness' Can Begin in Your 30s–40s — A New Early Sign of Dementia
The University of Cambridge study found that subtle loss of memory precision — memories becoming less detailed and accurate —...
Mayo Clinic Tool Predicts Alzheimer’s Risk Years Before Symptoms — Who’s Most at Risk?
What happened: Mayo Clinic researchers created a model that estimates 10-year and lifetime risk of cognitive decline using br...
Nanoparticles Repair the Blood–Brain Barrier and Reverse Alzheimer’s Signs in Mice
Researchers at IBEC and West China Hospital developed supramolecular nanoparticles that mimic ligands for the LRP1 receptor t...
Daily Peanuts Linked to Small Increases in Brain Blood Flow and Verbal Memory in Older Adults
A randomized crossover trial of 31 healthy adults aged 60–75 found that eating 60 g of unsalted, skin‑roasted peanuts daily f...
Aging Scrambles Brain Protein Tags — Short Calorie Restriction Reverses Some Changes
The Leibniz Institute on Aging used mass spectrometry to compare brain proteins in young and old mice and found age-related c...
Speaking Multiple Languages Linked to Slower Brain Aging, Large European Study Finds
Large European analysis: Researchers used the SHARE dataset (86,000+ participants, ages 51–90) to calculate a "biobehavioral ...
Predicting Postpartum Depression: A New Blood Test, Hormone Clues, and Faster Treatments
Postpartum depression affects about 1 in 8 U.S. women and often begins in the weeks after childbirth when estrogen and proges...
Old Drug, New Hope: Arginine Reduces Alzheimer’s Plaques and Restores Cognition in Mice
This Japanese study found that orally administered arginine—an amino acid already used in some treatments—reduced amyloid‑bet...
Scientists Identify Microplastics in Human Brains — Found More Often in Dementia-Linked Tissue
Researchers investigating mysterious "glassy blobs" in brain tissue found they are composed of microplastics and nanoplastics...
Common Supplement Reduces Alzheimer’s Protein Clumps in Animal Tests — Promising but Early
Japanese researchers found that oral arginine reduced amyloid-beta plaques and improved behavioural and inflammatory markers ...
Scientists Identify Reversible Tau Clusters That Could Stop Alzheimer’s Before Symptoms Appear
Scientists led by Professor Rei Kurita discovered tiny, soft tau protein clusters that appear before the rigid fibrils linked...
New Study Finds 'Adulthood' Brain Stage Begins Around Age 32 — What That Means for Your Health
The University of Cambridge-led MRI study of 3,802 neurotypical participants identifies five functional brain epochs with tur...
Simple Molecule L10 Reverses Alzheimer’s-like Symptoms in Rats by Removing Excess Copper
The study reports that a simple molecule, L10, removes excess copper from beta-amyloid deposits and reverses Alzheimer’s-like...
Alzheimer's May Hijack Cellular Clocks — New Study Finds Clock-Controlled Genes Linked to Disease
The Washington University study shows that circadian rhythms regulate gene activity differently across brain cell types and h...
Two FDA-Approved Cancer Drugs, Combined, Reduce a Key Alzheimer’s Protein in Mice — 1.4M Health Records Helped Point the Way
UCSF researchers used gene-expression screening and 1.4 million anonymized health records to repurpose existing drugs for Alz...
How Low Doses of Hydrogen Sulfide May Protect the Aging Brain — Promising Mouse Study
Low, controlled doses of hydrogen sulfide — a gas the body produces naturally — improved memory and motor function by about 5...
New Blood Test Detects Chronic Fatigue Syndrome — Could It Be Adapted for Long COVID?
Researchers report a blood test that separated people with severe Chronic Fatigue Syndrome (47 patients) from 61 healthy cont...
Kentucky Researchers Convert Alzheimer’s Risk Gene to Protective Form in Mice — A Promising Proof of Concept
The University of Kentucky led a 22-person team that used gene editing to convert an Alzheimer’s risk form of the APOE gene t...
3-Minute Ultrasound 'Massage' Might Restore Memory — New Research Targets Tau Protein
Researchers report that a three-minute session of low-intensity focused ultrasound may stimulate neuronal microtubules and im...